2-Chloro-5-(chloromethyl)pyridine → 1'-((6-chloropyridin-3-yl)methyl)-6H-spiro[benzofuro[6,5-d][1,3]dioxole-7,3'-indolin]-2'-one

HRID 189123Notes

Reaction equation

HRID 189123 reaction equation
[CH3:31][C:32]1([CH3:33])[CH2:34][O:35][c:36]2[cH:37][c:38]3[c:51]([cH:52][c:53]21)[C:41]1([CH2:40][O:39]3)[c:42]2[c:43]([cH:44][cH:45][cH:46][cH:47]2)[NH:48][C:49]1=[O:50].[Cl:1][c:2]1[n:3][cH:4][c:5]([CH2:8][Cl:9])[cH:6][cH:7]1.[NH:10]1[C:11](=[O:30])[C:12]2([CH2:13][O:14][c:15]3[c:16]2[cH:17][c:18]2[c:19]([cH:23]3)[O:20][CH2:21][O:22]2)[c:24]2[cH:25][cH:26][cH:27][cH:28][c:29]21>>[Cl:1][c:2]1[n:3][cH:4][c:5]([CH2:8][N:10]2[C:11](=[O:30])[C:12]3([CH2:13][O:14][c:15]4[c:16]3[cH:17][c:18]3[c:19]([cH:23]4)[O:20][CH2:21][O:22]3)[c:24]3[cH:25][cH:26][cH:27][cH:28][c:29]32)[cH:6][cH:7]1

Participants

4

Reactant 3

HCID 1554792-Chloro-5-(chloromethyl)pyridineHCID 53375495spiro[furo[2,3-f][1,3]benzodioxole-7,3'-indol]-2'(1'H)-oneHCID 592634705,5-dimethyl-5,6-dihydrospiro[benzo[1,2-b:5,4-b']difuran-3,3'-indol]-2'(1H)-one

Product 1

HCID 592634431'-((6-chloropyridin-3-yl)methyl)-6H-spiro[benzofuro[6,5-d][1,3]dioxole-7,3'-indolin]-2'-one

Sources & evidence

ORD record
ord-fd0353461053446daaa5999c72fc4da3
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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