Benzaldehyde → N-Benzylidene(piperidin-4-yl)methanamine

Participants

Reaction Steps

Benzaldehyde (28.0 g; 0.264 mol) was added, dropwise, to a solution of 4-aminomethylpiperidine (30.2 g; 0.264 mol) in toluene (100 ml). The solution thus obtained was kept stirred at room temperature. After 3 h, the solvent was removed by evaporation at reduced pressure and the residue was taken up twice in toluene. 53.4 g of N-hexahydro-4-pyridinylmethyl-N-phenylmethylidenamine was thus obtained, and was used in subsequent reaction without further purification.

Provenance & Evidence