2-methyl-2H-indazole-3-carbonyl chloride → HCID 24946637, compound

HRID 1891306Notes

Reaction equation

HRID 1891306 reaction equation
[CH3:1][N:2]1[C:10]([C:11](Cl)=[O:12])=[C:9]2[C:4]([CH:5]=[CH:6][CH:7]=[CH:8]2)=[N:3]1.[F:14][C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=1[CH2:21][CH2:22][N:23]1[CH2:28][CH2:27][CH:26]([CH2:29][NH2:30])[CH2:25][CH2:24]1>>[F:14][C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=1[CH2:21][CH2:22][N:23]1[CH2:24][CH2:25][CH:26]([CH2:29][NH:30][C:11]([C:10]2[N:2]([CH3:1])[N:3]=[C:4]3[C:9]=2[CH:8]=[CH:7][CH:6]=[CH:5]3)=[O:12])[CH2:27][CH2:28]1

Participants

3

Reactant 2

HCID 75375822-methyl-2H-indazole-3-carbonyl chlorideHCID 43829405HCID 43829405, compound

Product 1

HCID 24946637HCID 24946637, compound

Procedure

The compound was obtained according to the procedure described in Example 7e) using as reactants 2-methyl-2H-indazole-3-carbonyl chloride (Example 1b) (880 mg; 4.5 mmol) and 1-[2-(2-fluorophenyl)ethyl]-4-piperidine methanamine (Example 12a) (1.06 g; 4.5 mmol).

Workup

  1. customThe compound was obtained

Sources & evidence

ORD record
ord-15b7c5e2ec6d4cb9926ac77a9dedd387
Source dataset
uspto-grants-2013_08
Patent number
US08507528B2

Reaction notes

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