3-Chloro-4-fluoroaniline → HCID 58332214, compound

HRID 1891408Notes

Reaction equation

HRID 1891408 reaction equation
[Br:1][C:2]1[CH:6]=[C:5]([C:7]([OH:9])=O)[O:4][N:3]=1.[Cl:10][C:11]1[CH:12]=[C:13]([CH:15]=[CH:16][C:17]=1[F:18])[NH2:14]>>[Br:1][C:2]1[CH:6]=[C:5]([C:7]([NH:14][C:13]2[CH:15]=[CH:16][C:17]([F:18])=[C:11]([Cl:10])[CH:12]=2)=[O:9])[O:4][N:3]=1

Participants

3

Reactant 2

HCID 97083-Chloro-4-fluoroanilineHCID 3277163-Bromoisoxazole-5-carboxylic acid

Product 1

HCID 58332214HCID 58332214, compound

Procedure

This material was prepared according to the procedure of Example 1, Step C, using 3-bromoisoxazole-5-carboxylic acid and 3-chloro-4-fluoro aniline as starting materials. MF=C10H5BrClFN2O2; LCMS calculated for C10H5BrClFN2O2 (M+H)+: m/z=319.

Workup

  1. customThis material was prepared

Sources & evidence

ORD record
ord-8243f3c9f296482a9282dca3422b9998
Source dataset
uspto-grants-2013_08
Patent number
US08507541B2

Reaction notes

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