Ethanolamine → HCID 58367099, compound

HRID 1891499Notes

Reaction equation

HRID 1891499 reaction equation
O[CH:2]1[C:10]2[C:5](=[C:6]([C:11]3[S:15][C:14]([C:16]4[CH:17]=[CH:18][C:19]([O:24][CH:25]([CH3:27])[CH3:26])=[C:20]([CH:23]=4)[C:21]#[N:22])=[CH:13][CH:12]=3)[CH:7]=[CH:8][CH:9]=2)[CH2:4][CH2:3]1.[CH2:28]([CH2:30][NH2:31])[OH:29]>>[OH:29][CH2:28][CH2:30][NH:31][CH:2]1[C:10]2[C:5](=[C:6]([C:11]3[S:15][C:14]([C:16]4[CH:17]=[CH:18][C:19]([O:24][CH:25]([CH3:26])[CH3:27])=[C:20]([CH:23]=4)[C:21]#[N:22])=[CH:13][CH:12]=3)[CH:7]=[CH:8][CH:9]=2)[CH2:4][CH2:3]1

Participants

3

Reactant 2

HCID 700EthanolamineHCID 53232877HCID 53232877, compound

Product 1

HCID 58367099HCID 58367099, compound

Procedure

Prepared using General Procedure 20 from 5-(5-(1-hydroxy-2,3-dihydro-1H-inden-4-yl)thiophen-2-yl)-2-isopropoxybenzonitrile and ethanolamine. LCMS-ESI (m/z) calculated for C25H26N2O2S: 418.2; found 419.1 [M+H]+, tR=2.73 min.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-2ce1260baf39454285b3bec339b78e7c
Source dataset
uspto-grants-2013_08
Patent number
US08507538B2

Reaction notes

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