Epichlorohydrin → HCID 86662489, compound

Participants

Reaction Steps

As shown in Chemical Formula 2, an ethanol solution in which 5.03 g (22.0 mmol) of 2-(glycidyloxy)-1-naphthoaldehyde (3) was thoroughly dissolved in 110 mL of ethanol was prepared. Separately, an aqueous solution in which 4.48 g (32.9 mmol) of sodium acetate trihydrate and 2.29 g (32.9 mmol) of hydroxylamine hydrochloride were dissolved in 110 mL of water was prepared. The aqueous solution was added to the ethanol solution and the resultant reaction mixture was stirred at room temperature for 4 hours to effect the reaction. Then, water was added to the reaction mixture and the resultant precipitate was recovered by filtration and was vacuum-dried to obtain 5.36 g (yield: 100%) of 2-(glycidyloxy)-1-naphthoaldehyde oxime (4) as a white powder.

Provenance & Evidence