反应详情

To a stirred solution of 4-bromocinnamic acid (16 g) in methanol (150 mL) was added thionyl chloride (30 mL) at 0° C. The reaction mixture was warmed to room temperature and refluxed for 3 hours. After cooling to room temperature the solvents were evaporated to dryness. The crude compound obtained was used as such for the next step.

1. temperaturerefluxed for 3 hours
2. temperatureAfter cooling to room temperature the solvents
3. customwere evaporated to dryness