Hydrazine → HCID 67083086, compound

HRID 1892269Notes

Reaction equation

HRID 1892269 reaction equation
Cl[C:2]1[CH:11]=[C:10]([CH:12]([CH3:14])[CH3:13])[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[N:3]=1.[NH2:15][NH2:16]>>[NH:15]([C:2]1[CH:11]=[C:10]([CH:12]([CH3:14])[CH3:13])[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[N:3]=1)[NH2:16]

Participants

3

Reactant 2

HCID 9321HydrazineHCID 59283440HCID 59283440, compound

Product 1

HCID 67083086HCID 67083086, compound

Procedure

A solution of 2-chloro-4-isopropylquinoline (1.80 g, 8.8 mmol) in NH2NH2 was reacted as outlined in Scheme 1 above to give the desired title compound. Spectroscopic data: 1H NMR (300 MHz, CDCl3) δ ppm 1.41 (d, J=6.74 Hz, 6 H) 3.51-3.76 (m, 1 H) 7.20-7.35 (m, 1 H) 7.44-7.60 (m, 2 H) 7.61-7.79 (m, 1 H) 7.84-8.06 (m, 1 H).

Sources & evidence

ORD record
ord-fbb79094f09e4bb69b129f11537b3702
Source dataset
uspto-grants-2013_08
Patent number
US08507682B2

Reaction notes

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