Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
6-Amino-3-chloropyridazine → [2-(6-Chloro-3-pyridazinyl)-2-azavinyl]dimethylamine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 6-Amino-3-chloropyridazine | HCID 21643 | — |
| 반응물 | Dimethylformamide dimethyl acetal | HCID 78373 | — |
| 생성물 | [2-(6-Chloro-3-pyridazinyl)-2-azavinyl]dimethylamine | HCID 6802247 | 81.2% |
반응 단계
A mixture of 3-amino-6-chloropyridazine (1.3 g, 10 mmol) and dimethylformamide dimethylacetal (1.35 mL, 10.2 mmol) was heated at reflux for 2 h and concentrated in vacuo to afford a brown solid. After recrystallization with EtOAc, 1.5 g of N′-(6-chloro-pyridazin-3-yl)-N,N-dimethyl-formamidine was obtained in 81% yield.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08507676B2 |
| 출처 데이터셋 | uspto-grants-2013_08 |
| ORD ID | ord-4c9fafae15d34bd4a32279fc981c3b1f |
| 출처 메모 | uspto-grants-2013_08 |