HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Hydroxide → 4-(Methoxycarbonyl)pyridine-2-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | Dimethyl pyridine-2,4-dicarboxylate | HCID 254545 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 4-(Methoxycarbonyl)pyridine-2-carboxylic acid | HCID 13353752 | 99.5% |
Reaction Steps
A mixture of methanol (800 mL), potassium hydroxide (44 g, 0.95 mol) and dimethyl pyridine-2,4-dicarboxylate (ChemPacific) (156 g, 079 mol) was refluxed for 0.5 hours and then evaporated in vacuo to afford 4-(methoxycarbonyl)picolinic acid (144 g) as a yellow solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08507681B2 |
| Source dataset | uspto-grants-2013_08 |
| ORD ID | ord-5bc177a810a9483585be69c585405933 |
| Source note | uspto-grants-2013_08 |