Methyl 4-(3-bromo-4-oxobutyl)benzoate → HCID 178497709, compound

HRID 1892628Notes

Reaction equation

HRID 1892628 reaction equation
Br[CH:2]([CH2:5][CH2:6][C:7]1[CH:12]=[CH:11][C:10]([C:13]([O:15][CH3:16])=[O:14])=[CH:9][CH:8]=1)[CH:3]=O.[NH2:17][C:18]1[N:23]=[C:22]([NH2:24])[CH:21]=[C:20]([OH:25])[N:19]=1>>[NH2:17][C:18]1[NH:23][C:22]2[NH:24][CH:3]=[C:2]([CH2:5][CH2:6][C:7]3[CH:12]=[CH:11][C:10]([C:13]([O:15][CH3:16])=[O:14])=[CH:9][CH:8]=3)[C:21]=2[C:20](=[O:25])[N:19]=1

Participants

3

Reactant 2

HCID 15284221Methyl 4-(3-bromo-4-oxobutyl)benzoateHCID 178507952HCID 178507952, compound

Product 1

HCID 178497709HCID 178497709, compound

Procedure

reacting 2-bromo-4-(4-carbomethoxyphenyl)butanal with 2,4-diamino-6-hydroxypyrimidine to give methyl 4-[2-(2-amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoate;

Sources & evidence

ORD record
ord-9382fb90555b4c4a9c1e3c5930ed2475
Source dataset
uspto-grants-2013_08
Patent number
US08507716B2

Reaction notes

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