HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → D-Pemetrexed disodium
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | HCID 178471564 | HCID 178471564 | — |
| Product | D-Pemetrexed disodium | HCID 135625269 | — |
Reaction Steps
reacting N-[4-[2-(2-amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl-L-glutamic acid diethyl ester p-toluenesulfonate salt with sodium hydroxide to give pemetrexed disodium.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08507716B2 |
| Source dataset | uspto-grants-2013_08 |
| ORD ID | ord-60d86b3b3f2248eababec945432a1cbd |
| Source note | uspto-grants-2013_08 |