Methyl 4-bromobenzoate → Methyl 4-(4-oxobutyl)benzoate

HRID 1892631Notes

Reaction equation

HRID 1892631 reaction equation
Br[C:2]1[CH:11]=[CH:10][C:5]([C:6]([O:8][CH3:9])=[O:7])=[CH:4][CH:3]=1.[CH2:12]([OH:16])[CH2:13][CH:14]=[CH2:15]>>[C:6]([C:5]1[CH:10]=[CH:11][C:2]([CH2:15][CH2:14][CH2:13][CH:12]=[O:16])=[CH:3][CH:4]=1)([O:8][CH3:9])=[O:7]

Participants

3

Reactant 2

HCID 12081Methyl 4-bromobenzoateHCID 693893-Buten-1-ol

Product 1

HCID 9859111Methyl 4-(4-oxobutyl)benzoate

Procedure

condensing methyl p-bromobenzoate with 3-buten-1-ol; extracting the reaction mixture with an organic solvent to obtain an organic extract; decolorizing the organic extract with silica gel, and then removing the organic solvent to give 4-(4-carbomethoxyphenyl) butanal.

Workup

  1. extractionextracting the reaction mixture with an organic solvent
  2. customto obtain an organic extract
  3. extractionorganic extract with silica gel
  4. customremoving the organic solvent

Sources & evidence

ORD record
ord-64426e8617f04b7c9ad514159d276864
Source dataset
uspto-grants-2013_08
Patent number
US08507716B2

Reaction notes

Loading…