HCID 67388032, compound → HCID 58453206, compound

Participants

Reaction Steps

The 8-{4-[(E)-2-(4-propylcyclohexyl)ethenyl]phenyl}-1,4-dioxaspiro[4.5]dec-7-en (6.1 g, 16.64 mmol) was dissolved in a mixture of toluene and ethanol (toluene:EtOH=1:3). Pd/C (0.14 g) was added to 200 mL of the resulting solution and hydrogenated for 4 days. After reaction, Pd/C was removed by filtration, and the residue was purified column chromatography (hexane:ether=8:1) to obtain 8-{4-[2-(4-propylcyclohexyl)ethyl]phenyl}-1,4-dioxaspiro[4.5]decane (4.40 g, 72%).

Provenance & Evidence