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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1893169Generated: November 2, 2026

4-Hydroxybenzaldehyde → Benzaldehyde, 4-(phenylmethoxy)-

https://huagongshe.com/reaction/1893169

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-HydroxybenzaldehydeHCID 126—
ReactantBenzyl BromideHCID 7498—
ReactantPotassium CarbonateHCID 11430—
SolventAcetoneHCID 180—
ProductBenzaldehyde, 4-(phenylmethoxy)-HCID 78109—

Reaction Steps

4-hydroxy-benzaldehyde (57.64 g, 0.47 mol) and potassium carbonate (71.6 g, 0.51 mol), which were combined in acetone (200 mL), were reacted with benzyl bromine (80.73 g, 0.51 mol) and stirred at room temperature over night. The acetone was removed in vacuo, and the 4-Benzyloxy-benzaldehyde (71.6 g), as a white solid, is crystallized form ethyl acetate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08513233B2
Source datasetuspto-grants-2013_08
ORD IDord-3400494bb96f44b3bb56b195696f21fd
Source noteuspto-grants-2013_08