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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1893229Generated: October 29, 2026

N-(azetidin-3-ylcarbamoylmethyl)-3-trifluoromethyl-benzamide → HCID 49763683, compound

https://huagongshe.com/reaction/1893229

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-(azetidin-3-ylcarbamoylmethyl)-3-trifluoromethyl-benzamideHCID 59361594—
ReactantHCID 59541950HCID 59541950—
ProductHCID 49763683HCID 49763683—

Reaction Steps

The title compounds were prepared as white solids from hydrogenation of 5-(4-oxo-cyclohex-1-enyl)-3H-benzothiazol-2-one (as prepared in the previous step) followed by reductive amination of the corresponding ketone with N-(azetidin-3-ylcarbamoylmethyl)-3-trifluoromethyl-benzamide (as prepared in step B of Example 4) using the procedures described in Step C of Example 5 and Step C of Example 4.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08513229B2
Source datasetuspto-grants-2013_08
ORD IDord-fef2982f0e1b480284ad6fafa8b30a5f
Source noteuspto-grants-2013_08