Methyl 4-(4-oxocyclohexyl)benzoate → 4-(4-{3-[2-(3-Trifluoromethyl-benzoylamino)-acetylamino]-azetidin-1-yl}-cyclohexyl)-benzoic acid methyl ester

Participants

Reaction Steps

The title compound was prepared as a white solid by reductive amination of 4-(4-oxo-cyclohexyl)-benzoic acid methyl ester (as prepared in the previous step) and N-(azetidin-3-ylcarbamoylmethyl)-3-trifluoromethyl-benzamide (as prepared in step B of Example 4) using the procedure described in Step C of Example 4.

Provenance & Evidence