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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1893241Generated: November 1, 2026

N-(azetidin-3-ylcarbamoylmethyl)-3-trifluoromethyl-benzamide → HCID 49763931, compound

https://huagongshe.com/reaction/1893241

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-(azetidin-3-ylcarbamoylmethyl)-3-trifluoromethyl-benzamideHCID 59361594—
ReactantHCID 59541931HCID 59541931—
ProductHCID 49763931HCID 49763931—

Reaction Steps

The title compound was prepared as a white solid by hydrogenation of 4-(3H-benzoimidazol-5-yl)-cyclohex-3-enone (as prepared in the previous step) using the procedure described in Step C of Example 5 followed by reductive amination of the ketone with N-(azetidin-3-ylcarbamoylmethyl)-3-trifluoromethyl-benzamide (as prepared in step B of Example 4) using the procedure described in Step C of Example 4.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08513229B2
Source datasetuspto-grants-2013_08
ORD IDord-c8945495363a4f47b612f89318194472
Source noteuspto-grants-2013_08