HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(4-Oxocyclohexyl)benzonitrile → N-({1-[4-(4-Cyano-phenyl)-cyclohexyl]-azetidin-3-ylcarbamoyl}-methyl)-3-trifluoromethyl-benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(4-Oxocyclohexyl)benzonitrile | HCID 15789913 | — |
| Reactant | N-(azetidin-3-ylcarbamoylmethyl)-3-trifluoromethyl-benzamide | HCID 59361594 | — |
| Product | N-({1-[4-(4-Cyano-phenyl)-cyclohexyl]-azetidin-3-ylcarbamoyl}-methyl)-3-trifluoromethyl-benzamide | HCID 49764193 | — |
Reaction Steps
The title compound was prepared as a white solid by the reductive amination of 4-(4-oxo-cyclohexyl)-benzonitrile and N-(azetidin-3-ylcarbamoylmethyl)-3-trifluoromethyl-benzamide (as prepared in step B of Example 4) using the procedure described in Step C of Example 4.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08513229B2 |
| Source dataset | uspto-grants-2013_08 |
| ORD ID | ord-b37c600bf970440abca075570b0d3dd5 |
| Source note | uspto-grants-2013_08 |