4-Benzo[1,3]dioxol-5-yl-4-hydroxycyclohexanone → N-{[1-(4-Benzo[1,3]dioxol-5-yl-4-hydroxy-cyclohexyl)-azetidin-3-ylcarbamoyl]-methyl}-3-trifluoromethyl-benzamide

Participants

Reaction Steps

The title compound was prepared as a white solid by reductive amination of 4-benzo[1,3]dioxol-5-yl-4-hydroxy-cyclohexanone (as prepared in Example 1, Step B) and N-(azetidin-3-ylcarbamoylmethyl)-3-trifluoromethyl-benzamide (as prepared in step B of Example 4) using the procedure described in Step C of Example 4.

Provenance & Evidence