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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1893259Generated: October 31, 2026

4-Hydroxy-4-(3-methoxyphenyl)cyclohexan-1-one → HCID 49764444, compound

https://huagongshe.com/reaction/1893259

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Hydroxy-4-(3-methoxyphenyl)cyclohexan-1-oneHCID 23105862—
ReactantN-(azetidin-3-ylcarbamoylmethyl)-3-trifluoromethyl-benzamideHCID 59361594—
ProductHCID 49764444HCID 49764444—

Reaction Steps

The title compound was prepared as a white solid by reductive amination of 4-hydroxy-4-(3-methoxy-phenyl)-cyclohexanone (as prepared in the previous step) and N-(azetidin-3-ylcarbamoylmethyl)-3-trifluoromethyl-benzamide (as prepared in step B of Example 4) using the procedure described in Step C of Example 4.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08513229B2
Source datasetuspto-grants-2013_08
ORD IDord-7a826dc6ef164b15b91fdf895dee49e4
Source noteuspto-grants-2013_08