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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1893263Generated: October 25, 2026

1,4-Dioxaspiro[4.5]decan-8-one → 8-[4-(tert-Butyl-dimethyl-silanyloxy)-phenyl]-1,4-dioxa-spiro[4.5]decan-8-ol

https://huagongshe.com/reaction/1893263

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,4-Dioxaspiro[4.5]decan-8-oneHCID 567415—
Reactant(4-Bromophenoxy)(tert-butyl)dimethylsilaneHCID 4227167—
Product8-[4-(tert-Butyl-dimethyl-silanyloxy)-phenyl]-1,4-dioxa-spiro[4.5]decan-8-olHCID 59541982—

Reaction Steps

The title compound was prepared as a white solid from (4-bromo-phenoxy)-tert-butyl-dimethyl-silane (Aldrich) and 1,4-dioxa-spiro[4.5]decan-8-one using the procedure described in Step A of Example 1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08513229B2
Source datasetuspto-grants-2013_08
ORD IDord-4d8f79bf60fe462396770706787e83d9
Source noteuspto-grants-2013_08