Tetrabutylammonium Fluoride → HCID 59541974, compound

HRID 1893267Notes

Reaction equation

CCCC[N+](CCCC)(CCCC)CCCC.[F-].C([Si](C)(C)[O:24][C:25]1[CH:30]=[CH:29][C:28]([C:31]2([OH:38])[CH2:36][CH2:35][C:34](=[O:37])[CH2:33][CH2:32]2)=[CH:27][CH:26]=1)(C)(C)C>>[OH:38][C:31]1([C:28]2[CH:27]=[CH:26][C:25]([OH:24])=[CH:30][CH:29]=2)[CH2:32][CH2:33][C:34](=[O:37])[CH2:35][CH2:36]1

Participants

Reactant 2

HCID 2724141Tetrabutylammonium Fluoride

HCID 59541932HCID 59541932, compound

Product 1

HCID 59541974HCID 59541974, compound

Procedure

The title compound was prepared as a white solid by TBAF de-protection of 4-[4-(tert-butyl-dimethyl-silanyloxy)-phenyl]-4-hydroxy-cyclohexanone using the procedure described in Step D of Example 40.

Sources & evidence

ORD record: ord-078d60af3d094e149e09e3c38fd5055f
Source dataset: uspto-grants-2013_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08513229B2

Reaction notes

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