Tetrabutylammonium Fluoride → HCID 59541988, compound

HRID 1893270Notes

Reaction equation

HRID 1893270 reaction equation
CCCC[N+](CCCC)(CCCC)CCCC.[F-].C([Si](C)(C)[O:24][C:25]1[CH:26]=[C:27]([C:31]2([OH:38])[CH2:36][CH2:35][C:34](=[O:37])[CH2:33][CH2:32]2)[CH:28]=[CH:29][CH:30]=1)(C)(C)C>>[OH:38][C:31]1([C:27]2[CH:28]=[CH:29][CH:30]=[C:25]([OH:24])[CH:26]=2)[CH2:32][CH2:33][C:34](=[O:37])[CH2:35][CH2:36]1

Participants

3

Reactant 2

HCID 2724141Tetrabutylammonium FluorideHCID 59541960HCID 59541960, compound

Product 1

HCID 59541988HCID 59541988, compound

Procedure

The title compound was prepared as a white solid by TBAF de-protection of 4-[3-(tert-butyl-dimethyl-silanyloxy)-phenyl]-4-hydroxy-cyclohexanone (as prepared in the previous step) using the procedure described in Step D of Example 40.

Workup

  1. customas prepared in the previous step)

Sources & evidence

ORD record
ord-345501abcbb34338bc166b0b26d70c60
Source dataset
uspto-grants-2013_08
Patent number
US08513229B2

Reaction notes

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