4-(4-Fluorophenyl)-4-hydroxycyclohexan-1-one → N-({1-[4-(4-Fluoro-phenyl)-4-hydroxy-cyclohexyl]-azetidin-3-ylcarbamoyl}-methyl)-3-trifluoromethyl-benzamide

Participants

Reaction Steps

The title compound was prepared as a white solid by reductive amination of 4-(4-fluoro-phenyl)-4-hydroxy-cyclohexanone (as prepared in the previous step) and N-(azetidin-3-ylcarbamoylmethyl)-3-trifluoromethyl-benzamide (as prepared in step B of Example 4) using the procedure described in Step C of Example 4.

Provenance & Evidence