1,4-Dioxaspiro[4.5]decan-8-one → HCID 59541954, compound

HRID 1893276Notes

Reaction equation

HRID 1893276 reaction equation
Br[C:2]1[CH:7]=[CH:6][C:5]([C:8]#[C:9][Si:10]([CH3:13])([CH3:12])[CH3:11])=[CH:4][CH:3]=1.[O:14]1[C:18]2([CH2:23][CH2:22][C:21](=[O:24])[CH2:20][CH2:19]2)[O:17][CH2:16][CH2:15]1>>[CH3:11][Si:10]([C:9]#[C:8][C:5]1[CH:4]=[C:3]([C:21]2([OH:24])[CH2:22][CH2:23][C:18]3([O:17][CH2:16][CH2:15][O:14]3)[CH2:19][CH2:20]2)[CH:2]=[CH:7][CH:6]=1)([CH3:13])[CH3:12]

Participants

3

Reactant 2

HCID 5674151,4-Dioxaspiro[4.5]decan-8-oneHCID 4226980(4-Bromophenylethynyl)trimethylsilane

Product 1

HCID 59541954HCID 59541954, compound

Procedure

The title compound was prepared as a white solid from (4-bromo-phenylethynyl)-trimethyl-silane (Aldrich) and 1,4-dioxa-spiro[4.5]decan-8-one using the procedure described in Step A of Example 1.

Sources & evidence

ORD record
ord-9215223b37224699ade7fdc05876090a
Source dataset
uspto-grants-2013_08
Patent number
US08513229B2

Reaction notes

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