HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tetrabutylammonium Fluoride → HCID 49764704, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tetrabutylammonium Fluoride | HCID 2724141 | — |
| Reactant | N-(azetidin-3-ylcarbamoylmethyl)-3-trifluoromethyl-benzamide | HCID 59361594 | — |
| Reactant | HCID 59541958 | HCID 59541958 | — |
| Product | HCID 49764704 | HCID 49764704 | — |
Reaction Steps
The title compound was prepared as a white solid by reductive amination of 4-hydroxy-4-(3-trimethylsilanylethynyl-phenyl)-cyclohexanone (as prepared in the previous step) and N-(azetidin-3-ylcarbamoylmethyl)-3-trifluoromethyl-benzamide (as prepared in step B of Example 4) using the procedure described in Step C of Example 4 followed by a TBAF work-up using the procedure described in Step D of Example 40.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08513229B2 |
| Source dataset | uspto-grants-2013_08 |
| ORD ID | ord-8be0c24b1cd34d9b8ce4d7e897e91ab1 |
| Source note | uspto-grants-2013_08 |