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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1893279Generated: November 3, 2026

4-(4-CHLOROPHENYL)-4-HYDROXYCYCLOHEXANONE → HCID 49764828, compound

https://huagongshe.com/reaction/1893279

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(4-CHLOROPHENYL)-4-HYDROXYCYCLOHEXANONEHCID 10955227—
ReactantN-(azetidin-3-ylcarbamoylmethyl)-3-trifluoromethyl-benzamideHCID 59361594—
ProductHCID 49764828HCID 49764828—

Reaction Steps

The title compound was prepared as a white solid by reductive amination of 4-(4-chloro-phenyl)-4-hydroxy-cyclohexanone (as prepared in the previous step) and N-(azetidin-3-ylcarbamoylmethyl)-3-trifluoromethyl-benzamide (as prepared in step B of Example 4) using the procedure described in Step C of Example 4.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08513229B2
Source datasetuspto-grants-2013_08
ORD IDord-b9ace450361a45b5b46da52b698c85d5
Source noteuspto-grants-2013_08