1,4-Dioxaspiro[4.5]decan-8-one → HCID 59541953, compound

HRID 1893291Notes

Reaction equation

HRID 1893291 reaction equation
Br[C:2]1[CH:13]=[CH:12][C:5]2[N:6]([CH3:11])[C:7](=[O:10])[N:8]([CH3:9])[C:4]=2[CH:3]=1.[O:14]1[C:18]2([CH2:23][CH2:22][C:21](=[O:24])[CH2:20][CH2:19]2)[O:17][CH2:16][CH2:15]1>>[OH:24][C:21]1([C:2]2[CH:13]=[CH:12][C:5]3[N:6]([CH3:11])[C:7](=[O:10])[N:8]([CH3:9])[C:4]=3[CH:3]=2)[CH2:22][CH2:23][C:18]2([O:14][CH2:15][CH2:16][O:17]2)[CH2:19][CH2:20]1

Participants

3

Reactant 2

HCID 5674151,4-Dioxaspiro[4.5]decan-8-oneHCID 470034475-Bromo-1,3-dihydro-1,3-dimethyl-2H-benzimidazol-2-one

Product 1

HCID 59541953HCID 59541953, compound

Procedure

The title compound was prepared as a white solid from 5-bromo-1,3-dimethyl-1,3-dihydro-benzoimidazol-2-one (prepared by methylation of 5-bromo-1,3-dihydro-benzoimidazol-2-one from Pharmlab) and 1,4-dioxa-spiro[4.5]decan-8-one using the procedure described in Step A of Example 1.

Sources & evidence

ORD record
ord-58dc390aa61d4c8cb80d8e81775fdc98
Source dataset
uspto-grants-2013_08
Patent number
US08513229B2

Reaction notes

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