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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1893299Generated: October 26, 2026

4-Phenylcyclohexanone → [1-(4-Phenyl-cyclohexyl)-azetidin-3-yl]-carbamic acid tert-butyl ester

https://huagongshe.com/reaction/1893299

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-PhenylcyclohexanoneHCID 78605—
Reactant3-Aminoazetidine, 3-BOC protectedHCID 1519405—
Product[1-(4-Phenyl-cyclohexyl)-azetidin-3-yl]-carbamic acid tert-butyl esterHCID 59541918—

Reaction Steps

The title compound was prepared as a white solid by reductive amination of 4-phenyl-cyclohexanone and azetidin-3-yl-carbamic acid tert-butyl ester using the procedure described in Step D of Example 1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08513229B2
Source datasetuspto-grants-2013_08
ORD IDord-fa4d51a67a91493a9541ce32c23f384f
Source noteuspto-grants-2013_08