HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → (4-Phenyl-cyclohexyl)-azetidin-3-ylamine TFA Salt
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | [1-(4-Phenyl-cyclohexyl)-azetidin-3-yl]-carbamic acid tert-butyl ester | HCID 59541918 | — |
| Product | (4-Phenyl-cyclohexyl)-azetidin-3-ylamine TFA Salt | HCID 86646680 | — |
Reaction Steps
The title compound was prepared as colorless oil from the TFA de-protection of [1-(4-phenyl-cyclohexyl)-azetidin-3-yl]-carbamic acid tert-butyl ester (as prepared in the previous step) using the procedure described in Step E of Example 1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08513229B2 |
| Source dataset | uspto-grants-2013_08 |
| ORD ID | ord-5a3ca7c057f6405d837d155fb0caf671 |
| Source note | uspto-grants-2013_08 |