Methylamine → HCID 178485278, compound

Participants

Reaction Steps

A solution of 5-[4-(3-Hydroxy-propylamino)-7-trifluoromethyl-imidazo[1,2-a]quinoxalin-1-yl]-1H-pyrazole-3-carboxylic acid ethyl ester (0.02 mmol; 7 mg), Methylamine (0.40 mmol; 40% wt in H2O; 0.1 mL), in THF (0.2 mL), under argon was stirred at 35° C. for 48 hr. Concentration, then purification by preparative TLC (dichloromethane/methanol) afforded the title compound as a white solid (3 mg; 0.007 mmol; 44%).

Provenance & Evidence