HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Boc-1-methylhydrazine → 1,1-Dimethylethyl N-(2,5-dihydro-1H-pyrrol-1-yl)-N-methylcarbamate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Boc-1-methylhydrazine | HCID 3748280 | — |
| Reactant | 1,4-Dichloro-cis-2-butene | HCID 6432115 | — |
| Product | 1,1-Dimethylethyl N-(2,5-dihydro-1H-pyrrol-1-yl)-N-methylcarbamate | HCID 66881037 | 86.3% |
Reaction Steps
Using tert-butyl 1-methylhydrazinecarboxylate (5.00 g, 34.2 mmol) and (2Z)-1,4-dichloro-2-butene (3.6 ml, 34.2 mmol), and according to the method of Reference Example 35, step A, the title compound (5.85 g, yield 86%) was obtained as a yellow oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08513235B2 |
| Source dataset | uspto-grants-2013_08 |
| ORD ID | ord-301a903b86a34f378dd80de5f050e812 |
| Source note | uspto-grants-2013_08 |