Oxonium, trimethyl-, tetrafluoroborate(1-) (1:1) → HCID 66881356, compound

HRID 1893573Notes

Reaction equation

HRID 1893573 reaction equation
[CH2:1]([O:3][C:4](=[O:25])[CH2:5][N:6]([CH2:19][C:20]([O:22][CH2:23][CH3:24])=[O:21])[C:7]1[CH:15]=[C:14]2[C:10]([C:11]([CH2:16][CH3:17])=[N:12][NH:13]2)=[CH:9][C:8]=1[CH3:18])[CH3:2].F[B-](F)(F)F.[CH3:31][O+](C)C>>[CH2:1]([O:3][C:4](=[O:25])[CH2:5][N:6]([CH2:19][C:20]([O:22][CH2:23][CH3:24])=[O:21])[C:7]1[C:8]([CH3:18])=[CH:9][C:10]2[C:14]([CH:15]=1)=[N:13][N:12]([CH3:31])[C:11]=2[CH2:16][CH3:17])[CH3:2]

Participants

3

Reactant 2

HCID 2735153Oxonium, trimethyl-, tetrafluoroborate(1-) (1:1)HCID 178472736HCID 178472736, compound

Product 1

HCID 66881356HCID 66881356, compoundYield 33%

Procedure

Using the compound (722 mg, 2.08 mmol) of step C, and trimethyloxonium tetrafluoroborate (527 mg, 3.56 mmol), and according to the method of Reference Example 137, step F, the title compound (248 mg, yield 33%) was obtained as a yellow oil.

Sources & evidence

ORD record
ord-ae80183453ac4c868396c9f71913778e
Source dataset
uspto-grants-2013_08
Patent number
US08513235B2

Reaction notes

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