Cyclopropanol → Cyclopropylsulfamate

HRID 1893617Notes

Reaction equation

HRID 1893617 reaction equation
[C:1]1([O:7][S:8](=[O:11])(=[O:10])[NH2:9])[CH:6]=[CH:5]C=CC=1.[CH:12]1(O)[CH2:14][CH2:13]1>>[CH:12]1([NH:9][S:8](=[O:11])(=[O:10])[O-:7])[CH2:14][CH2:13]1.[CH:1]1([O:7][S:8](=[O:11])(=[O:10])[NH2:9])[CH2:5][CH2:6]1

Participants

4

Reactant 2

HCID 123361CyclopropanolHCID 11030308Phenylsulfamate

Product 2

HCID 21801555CyclopropylsulfamateHCID 57785190Cyclopropyl sulfamate

Procedure

Cyclopropylsulfamate was synthesized according to the method presented in the synthesis of sulfamic acid phenyl ester in Example 1 with the exception of utilizing cyclopropanol (synthesized by methods reported in JOC 1980, 45, 4129-35) to obtain sulfamic acid cyclopropyl ester.

Sources & evidence

ORD record
ord-f0dba5a8226f48ceb0536a19d496f4b1
Source dataset
uspto-grants-2013_08
Patent number
US08513186B2

Reaction notes

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