Phenylsulfamate → Sulfamic acid 1-isopropyl-cyclopropyl ester

HRID 1893639Notes

Reaction equation

HRID 1893639 reaction equation
[C:1]1([O:7][S:8](=[O:11])(=[O:10])[NH2:9])[CH:6]=[CH:5]C=[CH:3][CH:2]=1.[CH:12](C1(O)CC1)(C)C>>[CH:6]([C:1]1([O:7][S:8](=[O:10])(=[O:11])[NH2:9])[CH2:2][CH2:3]1)([CH3:5])[CH3:12]

Participants

3

Reactant 2

HCID 11030308PhenylsulfamateHCID 144356581-(Propan-2-yl)cyclopropan-1-ol

Product 1

HCID 57785237Sulfamic acid 1-isopropyl-cyclopropyl ester

Procedure

Sulfamic acid 1-isopropyl-cyclopropyl ester was synthesized according to the method presented in the synthesis of sulfamic acid phenyl ester in Example 1 with the exception of utilizing 1-isopropylcyclopropanol (synthesized by methods reported in Synthesis 1991, 234.) to obtain sulfamic acid 1-isopropyl-cyclopropyl ester.

Workup

  1. customSulfamic acid 1-isopropyl-cyclopropyl ester was synthesized

Sources & evidence

ORD record
ord-0fd7ce7e043d4cf4bf223b9c5dda5f50
Source dataset
uspto-grants-2013_08
Patent number
US08513186B2

Reaction notes

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