HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methyl-3-nitroanisole → 3-Methoxy-2-methylaniline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methyl-3-nitroanisole | HCID 78554 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 3-Methoxy-2-methylaniline | HCID 11804822 | 98% |
Reaction Steps
To 2-methyl-3-nitroanisole (5.02 g, 29.9 mmol) in EtOH (300 mL) was added Pd/C (0.50 g). The reaction was stirred under a H2 balloon overnight then filtered through celite to afford 3-methoxy-2-methylaniline (4.00 g, 98%). LCMS found 138.0 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08513186B2 |
| Source dataset | uspto-grants-2013_08 |
| ORD ID | ord-4071e8248e1c405b9ded7343022bb1c3 |
| Source note | uspto-grants-2013_08 |