2-Chloroaniline → HCID 178467000, compound

HRID 1893671Notes

Reaction equation

HRID 1893671 reaction equation
[CH2:1]([O:3][C:4]1[CH:13]=[C:12]([OH:14])[C:11]2[C:6](=[C:7](C)[C:8](OC)=[CH:9][CH:10]=2)[N:5]=1)[CH3:2].[Cl:18]C1C=CC=CC=1N>>[Cl:18][C:7]1[CH:8]=[CH:9][CH:10]=[C:11]2[C:6]=1[N:5]=[C:4]([O:3][CH2:1][CH3:2])[CH:13]=[C:12]2[OH:14]

Participants

3

Reactant 2

HCID 72402-ChloroanilineHCID 178467004HCID 178467004, compound

Product 1

HCID 178467000HCID 178467000, compound

Procedure

8-Chloro-2-ethoxy-quinolin-4-ol was synthesized according to the method presented in the synthesis of 2-ethoxy-7-methoxy-8-methyl-quinolin-4-ol in Example 137 with the exception of utilizing 2-chloro-aniline.

Sources & evidence

ORD record
ord-c037e359fb8444359a0aff66128a81f2
Source dataset
uspto-grants-2013_08
Patent number
US08513186B2

Reaction notes

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