2-Bromo-3-methoxyaniline → HCID 178467003, compound
Reaction equation
[CH2:1]([O:3][C:4]1[CH:13]=[C:12]([OH:14])[C:11]2[C:6](=[C:7](C)[C:8]([O:15][CH3:16])=[CH:9][CH:10]=2)[N:5]=1)[CH3:2].[Br:18]C1C(OC)=CC=CC=1N>>[Br:18][C:7]1[C:8]([O:15][CH3:16])=[CH:9][CH:10]=[C:11]2[C:6]=1[N:5]=[C:4]([O:3][CH2:1][CH3:2])[CH:13]=[C:12]2[OH:14]Participants
3
Procedure
8-Bromo-2-ethoxy-7-methoxy-quinolin-4-ol was synthesized according to the method presented in the synthesis of 2-ethoxy-7-methoxy-8-methyl-quinolin-4-ol in example 132 with the exception of utilizing 2-bromo-3-methoxy-aniline.
Sources & evidence
- ORD record
- ord-84da6963d7544ae9b7e22ae0095a0ad0
- Source dataset
- uspto-grants-2013_08
- Patent number
- US08513186B2
Reaction notes
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