HuagongsheHuagongshe Chemistry Print Report · For research reference only
Stannane, tributyl[5-(1,3-dioxolan-2-yl)-2-furanyl]- → (1-Benzyl-1H-indazol-5-yl)-[7-(5-(1,3-dioxolan-2-yl)-furan-2-yl)quinazolin-4-yl]amine Hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Stannane, tributyl[5-(1,3-dioxolan-2-yl)-2-furanyl]- | HCID 10960952 | — |
| Reactant | 1-benzyl-1H-indazol-5-yl(7-iodoquinazolin-4-yl)-amine hydrochloride | HCID 21952170 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | (1-Benzyl-1H-indazol-5-yl)-[7-(5-(1,3-dioxolan-2-yl)-furan-2-yl)quinazolin-4-yl]amine Hydrochloride | HCID 21951956 | — |
Reaction Steps
Prepared according to Procedure B from (1-benzyl-1H-indazol-5-yl)-(7-iodoquinazolin-4-yl)-amine hydrochloride and 5-(1,3-dioxolan-2-yl)-2-(tri-n-butylstannyl)furan; tlc Rf, 0.25 (100% EtOAc on silica); m/z (M+1+) 490.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08513262B2 |
| Source dataset | uspto-grants-2013_08 |
| ORD ID | ord-ec53b0c69fba42f3a85031a8c9c58010 |
| Source note | uspto-grants-2013_08 |