Water → HCID 58247405, compound

Participants

Reaction Steps

To a solution of Compound 17c (0.5 g; 1.6 mmol) in CH2Cl2 (6 mL) was added Et3N (0.72 mL; 6.4 mmol) and cyclopropylcarbonyl chloride (0.19 mL; 2.1 mmol). The solution was stirred at room temperature for 1 h, then poured the reaction mixture into water. Filtered to collect the solid and dried to afford Compound 17d (410 mg; 68% yield). MS: m/z 376.1 (M+H)+.

Provenance & Evidence