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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1894338Generated: November 1, 2026

1,4'-Bipiperidine → HCID 25262574, compound

https://huagongshe.com/reaction/1894338

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,4'-BipiperidineHCID 78607—
Reactantrac-(4S*,5R*)-2-(2-tert-butyl-4-ethoxy-pyrimidin-5-yl)-4,5-bis-(4-chloro-phenyl)-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl chlorideHCID 76588520—
ProductHCID 25262574HCID 25262574—

Reaction Steps

In a manner analogous to the method described in example 3, rac-(4S*,5R*)-2-(2-tert-butyl-4-ethoxy-pyrimidin-5-yl)-4,5-bis-(4-chloro-phenyl)-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl chloride was reacted with 4-piperidino-piperidine (Aldrich) to give the title compound as a racemic mixture. HR-MS (ES, m/z) calculated for C38H48N6O2Cl2 [(M+H)+] 691.3289, observed 691.3291.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08513239B2
Source datasetuspto-grants-2013_08
ORD IDord-75d89c3e130c4ac78c2cb59b5809c312
Source noteuspto-grants-2013_08