1-(2-(Methylsulfonyl)ethyl)piperazine → HCID 57670130, compound

Participants

Reaction Steps

In a manner analogous to the method described in example 3, rac-(4S*,5R*)-2-(2-tert-butyl-4-ethoxy-pyrimidin-5-yl)-4,5-bis-(4-chloro-phenyl)-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl chloride was reacted with 1-(2-methanesulfonyl-ethyl)-piperazine (prepared as described in Fotouhi, N. et al. WO 2005110996) to give the title compound. HR-MS (ES, m/z) calculated for C35H45N6O4SCl2 [(M+H)+] 715.2595, observed 715.259.

Provenance & Evidence