HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 67205042, compound → Hydrochloric Acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 67205042 | HCID 67205042 | — |
| Reactant | rac-(4S*,5R*)-2-(6-tert-butyl-4-ethoxy-pyridin-3-yl)-4,5-bis-(4-chloro-phenyl)-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl chloride | HCID 76588499 | — |
| Product | Hydrochloric Acid | HCID 313 | — |
| Product | HCID 25260865 | HCID 25260865 | — |
Reaction Steps
In a manner analogous to the method described in examples 8, rac-(4S*,5R*)-2-(6-tert-butyl-4-ethoxy-pyridin-3-yl)-4,5-bis-(4-chloro-phenyl)-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl chloride (example 7) was coupled with 1-((S)-2,2-dimethyl-[1,3]dioxolan-4-ylmethyl)-piperazine to give the title compound after deprotection with 2N hydrochloric acid. HR-MS (ES, m/z) calculated for C36H46N5O4Cl2 [(M+H)+] 682.2926, observed 682.2922.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08513239B2 |
| Source dataset | uspto-grants-2013_08 |
| ORD ID | ord-e8275db3927e43048d2f3cda931f7df9 |
| Source note | uspto-grants-2013_08 |