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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1894357Generated: November 3, 2026

HCID 67205042, compound → Hydrochloric Acid

https://huagongshe.com/reaction/1894357

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 67205042HCID 67205042—
Reactantrac-(4S*,5R*)-2-(6-tert-butyl-4-ethoxy-pyridin-3-yl)-4,5-bis-(4-chloro-phenyl)-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl chlorideHCID 76588499—
ProductHydrochloric AcidHCID 313—
ProductHCID 25260865HCID 25260865—

Reaction Steps

In a manner analogous to the method described in examples 8, rac-(4S*,5R*)-2-(6-tert-butyl-4-ethoxy-pyridin-3-yl)-4,5-bis-(4-chloro-phenyl)-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl chloride (example 7) was coupled with 1-((S)-2,2-dimethyl-[1,3]dioxolan-4-ylmethyl)-piperazine to give the title compound after deprotection with 2N hydrochloric acid. HR-MS (ES, m/z) calculated for C36H46N5O4Cl2 [(M+H)+] 682.2926, observed 682.2922.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08513239B2
Source datasetuspto-grants-2013_08
ORD IDord-e8275db3927e43048d2f3cda931f7df9
Source noteuspto-grants-2013_08