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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1894379Generated: November 3, 2026

N-(2-Methoxyethyl)-1-piperazineacetamide → HCID 25261510, compound

https://huagongshe.com/reaction/1894379

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-(2-Methoxyethyl)-1-piperazineacetamideHCID 7131115—
Reactant(4S,5R)-2-(6-tert-butyl-4-ethoxy-pyridin-3-yl)-4,5-bis-(4-chloro-phenyl)-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl chlorideHCID 57669958—
ProductHCID 25261510HCID 25261510—

Reaction Steps

In a manner analogous to the method described in examples 8, (4S,5R)-2-(6-tert-butyl-4-ethoxy-pyridin-3-yl)-4,5-bis-(4-chloro-phenyl)-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl chloride (example 51) was coupled with N-(2-methoxy-ethyl)-2-piperazin-1-yl-acetamide (Enamine) to give the title compound. HR-MS (ES, m/z) calculated for C38H49Cl2N6O4 [(M+H)+] 723.3187, observed 723.3191.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08513239B2
Source datasetuspto-grants-2013_08
ORD IDord-ea5c6a442d334a4d9e964a964f7eac52
Source noteuspto-grants-2013_08