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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1894380Generated: October 31, 2026

N-cyclopropyl-2-piperazin-1-ylacetamide → HCID 57669896, compound

https://huagongshe.com/reaction/1894380

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-cyclopropyl-2-piperazin-1-ylacetamideHCID 4962600—
Reactant(4S,5R)-2-(6-tert-butyl-4-ethoxy-pyridin-3-yl)-4,5-bis-(4-chloro-phenyl)-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl chlorideHCID 57669958—
ProductHCID 57669896HCID 57669896—

Reaction Steps

In a manner analogous to the method described in examples 8, (4S,5R)-2-(6-tert-butyl-4-ethoxy-pyridin-3-yl)-4,5-bis-(4-chloro-phenyl)-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl chloride (example 51) was coupled with N-cyclopropyl-2-piperazin-1-yl-acetamide (Enamine) to give the title compound. HR-MS (ES, m/z) calculated for C38H47Cl2N6O3 [(M+H)+] 705.3081, observed 705.308.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08513239B2
Source datasetuspto-grants-2013_08
ORD IDord-a4bbb38ab7824d0dbea8741a6edb60c0
Source noteuspto-grants-2013_08