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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1894381Generated: November 1, 2026

HCID 16228151, compound → HCID 25261513, compound

https://huagongshe.com/reaction/1894381

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 16228151HCID 16228151—
Reactant(4S,5R)-2-(6-tert-butyl-4-ethoxy-pyridin-3-yl)-4,5-bis-(4-chloro-phenyl)-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl chlorideHCID 57669958—
ProductHCID 25261513HCID 25261513—

Reaction Steps

In a manner analogous to the method described in examples 8, (4S,5R)-2-(6-tert-butyl-4-ethoxy-pyridin-3-yl)-4,5-bis-(4-chloro-phenyl)-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl chloride (example 51) was coupled with 1-piperazin-1-yl-2-tetrazol-1-yl-ethanone (Enamine) to give the title compound. HR-MS (ES, m/z) calculated for C36H41Cl2N9O3 [(M+H)+] 718.2782, observed 718.2788.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08513239B2
Source datasetuspto-grants-2013_08
ORD IDord-1145b4156086445d8cb5f90872d0e7fe
Source noteuspto-grants-2013_08