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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1894383Generated: November 4, 2026

HCID 16227147, compound → HCID 25261674, compound

https://huagongshe.com/reaction/1894383

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 16227147HCID 16227147—
Reactant(4S,5R)-2-(6-tert-butyl-4-ethoxy-pyridin-3-yl)-4,5-bis-(4-chloro-phenyl)-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl chlorideHCID 57669958—
ProductHCID 25261674HCID 25261674—

Reaction Steps

In a manner analogous to the method described in examples 8, (4S,5R)-2-(6-tert-butyl-4-ethoxy-pyridin-3-yl)-4,5-bis-(4-chloro-phenyl)-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl chloride (example 51) was coupled with (1-methyl-1H-pyrrol-2-yl)-piperazin-1-yl-methanone (Enamine) to give the title compound. HR-MS (ES, m/z) calculated for C39H45Cl2N6O3 [(M+H)+] 715.2925, observed 715.2926.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08513239B2
Source datasetuspto-grants-2013_08
ORD IDord-b28a89ee8055473897157823c7f2ca00
Source noteuspto-grants-2013_08