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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1894390Generated: November 4, 2026

HCID 7130769, compound → HCID 57670034, compound

https://huagongshe.com/reaction/1894390

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 7130769HCID 7130769—
Reactant(4S,5R)-2-(6-tert-butyl-4-ethoxy-pyridin-3-yl)-4,5-bis-(4-chloro-phenyl)-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl chlorideHCID 57669958—
ProductHCID 57670034HCID 57670034—

Reaction Steps

In a manner analogous to the method described in examples 8, (4S,5R)-2-(6-tert-butyl-4-ethoxy-pyridin-3-yl)-4,5-bis-(4-chloro-phenyl)-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl chloride (example 51) was coupled with 2-(4-methyl-thiazol-2-yl)-1-piperazin-1-yl-ethanone (Enamine) to give the title compound. HR-MS (ES, m/z) calculated for C39H45Cl2N6O3S [(M+H)+] 747.2646, observed 747.2642.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08513239B2
Source datasetuspto-grants-2013_08
ORD IDord-e9764404231c49748ac8caf15f1cab59
Source noteuspto-grants-2013_08