HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-Butyl 3,9-diazaspiro[5.5]undecane-3-carboxylate → HCID 25261825, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-Butyl 3,9-diazaspiro[5.5]undecane-3-carboxylate | HCID 15296367 | — |
| Reactant | (4S,5R)-2-(6-tert-butyl-4-ethoxy-pyridin-3-yl)-4,5-bis-(4-chloro-phenyl)-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl chloride | HCID 57669958 | — |
| Product | HCID 25261825 | HCID 25261825 | — |
Reaction Steps
In a manner analogous to the method described in examples 8, (4S,5R)-2-(6-tert-butyl-4-ethoxy-pyridin-3-yl)-4,5-bis-(4-chloro-phenyl)-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl chloride (example 51) was coupled with 3,9-diaza-spiro[5.5]undecane-3-carboxylic acid tert-butyl ester (Syntech Labs) to give the title compound. HR-MS (ES, m/z) calculated for C43H56Cl2N5O4 [(M+H)+] 776.3704, observed 776.3699.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08513239B2 |
| Source dataset | uspto-grants-2013_08 |
| ORD ID | ord-45d79dfce3ad486f97e94925b0a0b78e |
| Source note | uspto-grants-2013_08 |